Jorgie - make sure you visit St Kilda either on a sat or sun! It's a funky place! the beach is ok, there is luna park and loads of cool pubs/bars along the main strip and CAKES! OMG cakes galore!
Clubs - Um Taboo on Collins I think... Ladida on King St, there is another I don't recall the name oh wait The Loft - I think on Lonsdale... If you are up for it venture down the little lane ways - always little funky places in there.. we found a few, cannot remember names but they were always good... there are a few in Crown - not the greatest but easy to get too.
Visit the Velvet bar at Crown on the main gaming floor for a Supercocktail.. they are piss weak but the novelty is fun!
Definitely go to Lygon St - Italian food GALORE!!!
Queen Vic markets - Paddy's on crack... it's great for bargains but be warned after the first 5 aisles its all the same. There food market is great for getting a bunch of nice deli snacks and chilling out and eating.... Lollies stores too!
Shopping - well anywhere and everywhere DFO down at spencer st station is great! there is bourke st mall - check out the Basement at Myer on bourke st... ITS HUGEEEEEEEEEEEE! like the equivalent to two levels of pitt st myer! There is also Chapel Rd - that's a bit pricey though but some great boutiques! Friday night is late night shopping in melbourne so be warned its NOT thursday!